We measure how living human brain tissue changes over time, and how drugs change it.

Across development, ageing and disease, and under treatment.

The data trains models that predict what a compound will do before it reaches the clinic.

Science

Vale grows standardized human brain organoids and reads them repeatedly over time: imaging, functional activity and molecular readouts, on the same tissue, with and without treatment.

Every study produces a time-resolved, multimodal dataset, documented from protocol to output and ready for analysis.

We train predictive models on that data, for neurodevelopment, neurodegeneration and brain longevity.

From source to dataset

Source

Readouts

Series

Dataset

Imaging

[How structure changes, organoid by organoid.]

Functional activity

[How activity changes, timepoint by timepoint.]

Molecular readouts

[How expression changes, with and without treatment.]

Work with Vale

Custom studies

Custom
studies

A study designed around your program and run on our organoids under standardized conditions. You receive the full dataset, the experimental documentation and analysis-ready outputs.

Models available today: cortical, hippocampal, midbrain and spinal cord organoids, from healthy and disease-relevant genetic backgrounds. Choose the region your indication affects.

available now

Predictive models

Predictive
models

Compound-level predictions from models trained on Vale’s own data. The first models cover central nervous system indications, to compare candidates and reach a go/no-go decision earlier.

Until then, every custom study adds to the dataset those models learn from.

from 2027

Tell us about your CNS program
or how we can help.

Talk to the team

We measure how living human brain tissue changes over time, and how drugs change it.

Vale grows standardized human brain organoids and reads them repeatedly over time: imaging, functional activity and molecular readouts, on the same tissue, with and without treatment.

Vale grows standardized human brain organoids and reads them repeatedly over time: imaging, functional activity and molecular readouts, on the same tissue, with and without treatment.

Vale grows standardized human brain organoids and reads them repeatedly over time: imaging, functional activity and molecular readouts, on the same tissue, with and without treatment.

Vale grows standardized human brain organoids and reads them repeatedly over time: imaging, functional activity and molecular readouts, on the same tissue, with and without treatment.

Every study produces a time-resolved, multimodal dataset, documented from protocol to output and ready for analysis.

From source to dataset

Imaging

Functional activity

Molecular readouts

Custom studies

Customstudies

Predictive models

Predictivemodels

Tell us about your CNS programor how we can help.

Custom
studies

Predictive
models

Tell us about your CNS program
or how we can help.